Lectins are a large class of sugar-binding proteins that can be found in all forms of life. In plants, lectins are part of the natural defense against microorganisms, pests, and insects. Many members of the lectin protein family can agglutinate (clump together) and become problematic for human health.
Lectins have been thought to contribute to the development of diseases such as celiac disease, autoimmune diseases, rheumatoid arthritis, obesity, cardiovascular disease, and type 2 diabetes through mechanisms involving translocation across the intestinal barrier and activation of the adaptive immune system. [1,2] The most common high-lectin foods include: grains, legumes, and nightshades.
Aquaporins, or “water channels”, are membrane proteins that form pores to facilitate water transport between cells. Human aquaporins show similarity to aquaporins from food sources (e.g., spinach, soy, corn, tomato, etc.) which could trigger the production of antibodies, which might increase risk for neuro-autoimmune disorders. [3]
Lectin and aquaporin sensitivities are your body’s delayed immune response that can occur hours to days after these foods are consumed.
Symptoms associated with lectin and aquaporin food sensitivities include:
Risk factors that may place you at higher risk for lectin or aquaporin sensitivities include:
Major harmful effects of dietary lectins may include:
What Does the Vibrant Lectin Zoomer Include?
The Lectin Zoomer is a unique peptide-level test which detects IgA and IgG antibodies to lectins and aquaporins in the most comprehensive panel of foods available on the market.
Following is an example of a Food Sensitivity Test (protein level) and a Lectin/Aquaporin Zoomer panel (peptide level). Several foods on the Food Sensitivity test are negative but show up as reactive for IgG and IgA on the Lectin/Aquaporin Zoomer. This is a great example of why standard food sensitivity tests may not detect sensitivity to lectin components of foods.
The important to take away from this is that standard food sensitivity tests are whole protein or extract sensitivity tests, whereas the Vibrant Food Zoomers are peptide-level tests, which means that we are detecting sensitivity to the thousands of individual peptides in each food tested, in order to avoid cross-reactivity, the possibility of low stomach acid or pancreatic enzymes skewing results, or the role that intestinal permeability plays in whole proteins translocating across the intestinal barrier.
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